Sliwkowski, Mark X.: search on Z-Library

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1

Treatment of HER2-positive breast cancer: current status and future perspectives

Arteaga, Carlos L., Sliwkowski, Mark X., Osborne, C. Kent, Perez, Edith A., Puglisi, Fabio, Gianni, Luca

Journal:

Nature Reviews Clinical Oncology (formerly Nature Clinical Practice Oncology)

Year:

2011

Language:

english

File:

PDF, 3.26 MB

english, 2011

2

Preclinical pharmacokinetics of MEHD7945A, a novel EGFR/HER3 dual-action antibody, and prediction of its human pharmacokinetics and efficacious clinical dose

Amrita V. Kamath, Dan Lu, Priyanka Gupta, Denise Jin, Hong Xiang, Anne Wong, Cecilia Leddy, Lisa Crocker, Gabriele Schaefer, Mark X. Sliwkowski, Lisa A. Damico-Beyer

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2012

Language:

english

File:

PDF, 350 KB

english, 2012

3

Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941

Teemu T. Junttila, Robert W. Akita, Kathryn Parsons, Carter Fields, Gail D. Lewis Phillips, Lori S. Friedman, Deepak Sampath, Mark X. Sliwkowski

Journal:

Year:

2009

Language:

english

File:

PDF, 1.48 MB

english, 2009

4

Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941

Teemu T. Junttila, Robert W. Akita, Kathryn Parsons, Carter Fields, Gail D. Lewis Phillips, Lori S. Friedman, Deepak Sampath, Mark X. Sliwkowski

Journal:

Year:

2011

Language:

english

File:

PDF, 37 KB

english, 2011

5

Formation of a high affinity heregulin binding site using the soluble extracellular domains of ErbB2 with ErbB3 or ErbB4

V.Danial Fitzpatrick, Paul I Pisacane, Richard L Vandlen, Mark X Sliwkowski

Journal:

Year:

1998

Language:

english

File:

PDF, 152 KB

english, 1998

6

The Nature of Constitutive Activation of HER2 at the Single Molecule Level

Chung, Inhee, Akita, Robert, Shao, Lily, Schaefer, Gabriele, Sliwkowski, Mark, Mellman, Ira

Journal:

Biophysical Journal

Year:

2012

Language:

english

File:

PDF, 36 KB

english, 2012

7

[Methods in Enzymology] Sulfur and Sulfur Amino Acids Volume 143 || Assay of enzyme-catalyzed oxygen-dependent disulfide bond formation

Sliwkowski, Mark X.

Year:

1987

Language:

english

File:

PDF, 215 KB

english, 1987

8

Axon-Induced Mitogenesis of Human Schwann Cells Involves Heregulin and p185erbB2

Thomas K. Morrissey, Allan D. O. Levi, Andrew Nuijens, Mark X. Sliwkowski and Richard P. Bunge

Journal:

Proceedings of the National Academy of Sciences

Year:

1995

Language:

english

File:

PDF, 1.22 MB

english, 1995

9

Targeting ligand-activated ErbB2 signaling inhibits breast and prostate tumor growth

David B Agus, Robert W Akita, William D Fox, Gail D Lewis, Brian Higgins, Paul I Pisacane, Julie A Lofgren, Charles Tindell, Douglas P Evans, Krista Maiese, Howard I Scher, Mark X Sliwkowski

Journal:

Year:

2002

Language:

english

File:

PDF, 450 KB

english, 2002

10

Effects of in Vivo Heregulin β1 Treatment in Wild-Type and ErbB Gene-Targeted Mice Depend on Receptor Levels and Pregnancy

Sue O’Shea, Kent Johnson, Ross Clark, Mark X. Sliwkowski, Sharon L. Erickson

Journal:

The American Journal of Pathology

Year:

2001

Language:

english

File:

PDF, 3.30 MB

english, 2001

11

An Open-and-Shut Case? Recent Insights into the Activation of EGF/ErbB Receptors

Antony W Burgess, Hyun-Soo Cho, Charles Eigenbrot, Kathryn M Ferguson, Thomas P.J Garrett, Daniel J Leahy, Mark A Lemmon, Mark X Sliwkowski, Colin W Ward, Shigeyuki Yokoyama

Journal:

Year:

2003

Language:

english

File:

PDF, 504 KB

english, 2003

12

Neuregulin-3 (NRG3): A novel neural tissue-enriched protein that binds and activates ErbB4

Zhang, D., Sliwkowski, M. X., Mark, M., Frantz, G., Akita, R., Sun, Y., Hillan, K., Crowley, C., Brush, J., Godowski, P. J.

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 415 KB

english, 1997

13

Trastuzumab-DM1 (T-DM1) retains all the mechanisms of action of trastuzumab and efficiently inhibits growth of lapatinib insensitive breast cancer

Teemu T. Junttila, Guangmin Li, Kathryn Parsons, Gail Lewis Phillips, Mark X. Sliwkowski

Journal:

Breast Cancer Research and Treatment

Year:

2011

Language:

english

File:

PDF, 650 KB

english, 2011

14

AN IMPROVED METHOD FOR QUANTITATION OF SULFHYDRYL CONCENTRATION IN TURBID SAMPLES

MARK X. SLIWKOWSKI, J. JEFFREY STRANDHOLM, HAROLD E. SWAISGOOD

Journal:

Journal of Food Science

Year:

1980

Language:

english

File:

PDF, 358 KB

english, 1980

15

Selenoprotein A of the Clostridial Glycine Reductase Complex: Purification and Amino Acid Sequence of the Selenocysteine-Containing Peptide

Mark X. Sliwkowski and Thressa C. Stadtman

Journal:

Proceedings of the National Academy of Sciences

Year:

1988

Language:

english

File:

PDF, 968 KB

english, 1988

16

Regulation of the acetylcholine receptor ϵ subunit gene by recombinant ARIA: An in vitro model for transynaptic gene regulation

Gerald C Chu, Lisa M Moscoso, Mark X Sliwkowski, John P Merlie

Journal:

Year:

1995

Language:

english

File:

PDF, 4.68 MB

english, 1995

17

High-Resolution Solution Structure of the EGF-like Domain of Heregulin-α ‡

Jacobsen, Neil E., Abadi, Nasrin, Sliwkowski, Mark X., Reilly, Dorothea, Skelton, Nicholas J., Fairbrother, Wayne J.

Journal:

Year:

1996

Language:

english

File:

PDF, 805 KB

english, 1996

18

Neuregulin-3 (NRG3): A Novel Neural Tissue-Enriched Protein that Binds and Activates ErbB4

Dongxiao Zhang, Mark X. Sliwkowski, Melanie Mark, Gretchen Frantz, Robert Akita, Yang Sun, Kenneth Hillan, Craig Crowley, Jennifer Brush and Paul J. Godowski

Journal:

Proceedings of the National Academy of Sciences

Year:

1997

Language:

english

File:

PDF, 1.65 MB

english, 1997

19

Personalized drug combinations to overcome trastuzumab resistance in HER2-positive breast cancer

Vu, Thuy, Sliwkowski, Mark X., Claret, Francois X.

Journal:

Biochimica et Biophysica Acta (BBA) - Reviews on Cancer

Year:

2014

Language:

english

File:

PDF, 1.20 MB

english, 2014

20

Neuregulin-1 and Human Epidermal Growth Factor Receptors 2 and 3 Play a Role in Human Lung Development In Vitro

Patel, Neil V., Acarregui, Michael J., Snyder, Jeanne M., Klein, Jonathan M., Sliwkowski, Mark X., Kern, Jeffrey A.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Year:

2000

Language:

english

File:

PDF, 517 KB

english, 2000

21

Analysis of Heregulin-Induced ErbB2 Phosphorylation with a High-Throughput Kinase Receptor Activation Enzyme-Linked Immunosorbant Assay

Michael D. Sadick, Mark X. Sliwkowski, Andrew Nuijens, Laura Bald, Nancy Chiang, Julie A. Lofgren, Wai Lee T. Wong

Journal:

Analytical Biochemistry

Year:

1996

Language:

english

File:

PDF, 178 KB

english, 1996

22

Modeling the efficacy of trastuzumab-DM1, an antibody drug conjugate, in mice

Nelson L. Jumbe, Yan Xin, Douglas D. Leipold, Lisa Crocker, Debra Dugger, Elaine Mai, Mark X. Sliwkowski, Paul J. Fielder, Jay Tibbitts

Journal:

Journal of Pharmacokinetics and Pharmacodynamics

Year:

2010

Language:

english

File:

PDF, 729 KB

english, 2010

23

The biology of human epidermal growth factor receptor 2

Srividya Sundaresan, Elicia Penuel, Mark X. Sliwkowski

Journal:

Current Oncology Reports

Year:

1999

Language:

english

File:

PDF, 311 KB

english, 1999

24

Establishment of Schwann cell lines from normal adult and embryonic rat dorsal root ganglia

Rong-hao Li, Mark X. Sliwkowski, Jeannie Lo, Jennie P. Mather

Journal:

Journal of Neuroscience Methods

Year:

1996

Language:

english

File:

PDF, 8.27 MB

english, 1996

25

10.1038/35052073

Yarden, Yosef, Sliwkowski, Mark X.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2001

Language:

english

File:

PDF, 2.34 MB

english, 2001

26

Targeting cyclooxygenase 2 and her-2/neu pathways inhibits colorectal carcinoma growth

Moss Mann, Hongmiao Sheng, Jinyi Shao, Christopher S. Williams, Paul I. Pisacane, Mark X. Sliwkowski, Raymond N. Dubois

Journal:

Gastroenterology

Year:

2001

Language:

english

File:

PDF, 251 KB

english, 2001

27

Biological Response to ErbB Ligands in Nontransformed Cell Lines Correlates with a Specific Pattern of Receptor Expression

Sundaresan, Srividya, Roberts, Penelope E., King, Kathleen L., Sliwkowski, Mark X., Mather, Jennie P.

Journal:

Year:

1998

Language:

english

File:

PDF, 211 KB

english, 1998

28

Labeling of cysteine-containing peptides with 2-nitro-5-thiobenzoic acid

Mark X. Sliwkowski, Rodney L. Levine

Journal:

Analytical Biochemistry

Year:

1985

Language:

english

File:

PDF, 447 KB

english, 1985

29

Inhibitory effects of combinations of HER-2/neu antibody and chemotherapeutic agents used for treatment of human breast cancers

Pegram, Mark, Hsu, Sheree, Lewis, Gail, Pietras, Richard, Beryt, Malgorzata, Sliwkowski, Mark, Coombs, Daniel, Baly, Deborah, Kabbinavar, Fairooz, Slamon, Dennis

Journal:

Year:

1999

Language:

english

File:

PDF, 255 KB

english, 1999

30

Biologic effects of heregulin/neu differentiation factor on normal and malignant human breast and ovarian epithelial cells

Aguilar, Zuleima, Akita, Robert W, Finn, Richard S, Ramos, B Lillian, Pegram, Mark D, Kabbinavar, Fairooz F, Pietras, Richard J, Pisacane, Paul, Sliwkowski, Mark X, Slamon, Dennis J

Journal:

Year:

1999

Language:

english

File:

PDF, 351 KB

english, 1999

31

Heregulin enhances regenerative proliferation in postnatal rat utricular sensory epithelium after ototoxic damage

J. Lisa Zheng, Gretchen Frantz, Annette K. Lewis, Mark Sliwkowski, Wei-Qiang Gao

Journal:

Brain Cell Biology

Year:

1999

Language:

english

File:

PDF, 720 KB

english, 1999

32

Simultaneous single-step purification of thiolase and NADP-dependent 3-hydroxybutyryl-CoA dehydrogenase from Clostridium kluyveri

Mark X. Sliwkowski, Maris G.N. Hartmanis

Journal:

Analytical Biochemistry

Year:

1984

Language:

english

File:

PDF, 795 KB

english, 1984

33

Binding specificities and affinities of egf domains for ErbB receptors

Jennifer T Jones, Robert W Akita, Mark X Sliwkowski

Journal:

Year:

1999

Language:

english

File:

PDF, 118 KB

english, 1999

34

Development of Herceptin

Carter, Paul, Fendly, Brian M., Lewis, Gail D., Sliwkowski, Mark X.

Journal:

Year:

2000

Language:

english

File:

PDF, 155 KB

english, 2000

35

Mechanisms of Acquired Resistance to Trastuzumab Emtansine in Breast Cancer Cells

Li, Guangmin, Guo, Jun, Shen, Ben-Quan, Bumbaca Yadav, Daniela, Sliwkowski, Mark X., Crocker, Lisa M., Lacap, Jennifer A., Lewis Phillips, Gail D

Journal:

Molecular Cancer Therapeutics

Year:

2018

Language:

english

File:

PDF, 1.57 MB

english, 2018

36

γ-Heregulin: a novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175

Schaefer, Gabriele, Fitzpatrick, V Danial, Sliwkowski, Mark X

Journal:

Year:

1997

Language:

english

File:

PDF, 798 KB

english, 1997

37

Insights into ErbB signaling from the structure of the ErbB2-pertuzumab complex

Matthew C Franklin, Kendall D Carey, Felix F Vajdos, Daniel J Leahy, Abraham M de Vos, Mark X Sliwkowski

Journal:

Year:

2004

Language:

english

File:

PDF, 818 KB

english, 2004

38

Perspectives on Anti-HER Monoclonal Antibodies

Ranson, Malcolm, Sliwkowski, Mark X.

Journal:

Year:

2002

Language:

english

File:

PDF, 84 KB

english, 2002

39

Humanization of a recombinant monoclonal antibody to produce a therapeutic HER dimerization inhibitor, pertuzumab

Camellia W. Adams, David E. Allison, Kelly Flagella, Leonard Presta, Janet Clarke, Noel Dybdal, Kathleen McKeever, Mark X. Sliwkowski

Journal:

Cancer Immunology, Immunotherapy

Year:

2006

Language:

english

File:

PDF, 390 KB

english, 2006

40

Ready to partner

Sliwkowski, Mark X.

Journal:

Natural Structural Biology

Year:

2003

Language:

english

File:

PDF, 210 KB

english, 2003

41

Heregulins and the ErbB-2/3/4 receptors in gliomas

Manfred Westphal, Leonie Meima, Eva Szonyi, Julie Lofgren, Hildegard Meissner, Wolfgang Hamel, Karoly Nikolics, and Mark X. Sliwkowski

Journal:

Journal of Neuro-Oncology

Year:

1997

Language:

english

File:

PDF, 150 KB

english, 1997

42

Nonidentity of sulfhydryl oxidase and γ-glutamyltransferase in bovine milk

Mary B. Sliwkowski, Mark X. Sliwkowski, Harold E. Swaisgood, H.Robert Horton

Journal:

Archives of Biochemistry and Biophysics

Year:

1981

Language:

english

File:

PDF, 651 KB

english, 1981

43

High cell-surface density of HER2 deforms cell membranes

Chung, Inhee, Reichelt, Mike, Shao, Lily, Akita, Robert W., Koeppen, Hartmut, Rangell, Linda, Schaefer, Gabriele, Mellman, Ira, Sliwkowski, Mark X.

Journal:

Nature Communications

Year:

2016

Language:

english

File:

PDF, 5.86 MB

english, 2016

44

Trastuzumab Emtansine (T-DM1): A Novel Agent for Targeting HER2+ Breast Cancer

Howard A. Burris III, Jay Tibbitts, Scott N. Holden, Mark X. Sliwkowski, Gail D. Lewis Phillips

Journal:

Clinical Breast Cancer

Year:

2011

Language:

english

File:

PDF, 851 KB

english, 2011

45

Additive anti-neoplastic effect using combination therapy with anti-HER-2 antibodies and celecoxib

Moss Mann, Hongmiao Sheng, Mark Sliwkowsky, Raymond N. DuBois

Journal:

Gastroenterology

Year:

2000

Language:

english

File:

PDF, 192 KB

english, 2000

46

Membrane Deformation by HER2 Overexpression Disrupts Epithelial Integrity

Chung, Inhee, Reichelt, Mike, Dowbenko, Don, Mellman, Ira, Sliwkowski, Mark

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 47 KB

english, 2015

47

[Methods in Enzymology] Posttranslational Modifications Part B Volume 107 || Characterization of selenomethionine in proteins

Sliwkowski, Mark X.

Year:

1984

Language:

english

File:

PDF, 202 KB

english, 1984

48

Preclinical studies with Erlotinib (Tarceva)

Robert W. Akita, Mark X. Sliwkowski

Journal:

Seminars in Oncology

Year:

2003

Language:

english

File:

PDF, 174 KB

english, 2003

49

Catalytic effect of sulfhydryl oxidase on the formation of three-dimensional structure in chymotrypsinogen A

Violeta G. Janolino, Mark X. Sliwkowski, Harold E. Swaisgood, H.Robert Horton

Journal:

Archives of Biochemistry and Biophysics

Year:

1978

Language:

english

File:

PDF, 855 KB

english, 1978

50

Backbone dynamics of the EGF-like domain of heregulin-α

Wayne J. Fairbrother, Jun Liu, Paul I. Pisacane, Mark X. Sliwkowski, Arthur G. Palmer III

Journal:

Journal of Molecular Biology

Year:

1998

Language:

english

File:

PDF, 707 KB

english, 1998

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